BOTOX® for Overactive Bladder: Proven Results

Can BOTOX® really improve your Overactive Bladder (OAB) symptoms?
The results speak for themselves.

Patients receiving BOTOX® reported a significant reduction in the number of their daily leakage episodes.

BOTOX<sup>®</sup> (onabotulinumtoxinA) treatment results proven in two clinical trials

* Reduction of Urinary Incontinence (UI) episodes in:

Study 1: BOTOX® n = 280; placebo n = 277;

  • Patients with ≥50% reduction: BOTOX® 57.5%, placebo 28.9% (P <.001)
  • Patients with ≥75% reduction: BOTOX® 44.6%, placebo 15.2% (P <.001)
  • Patients with 100% reduction: BOTOX® 22.9%, placebo 6.5% (P <.001)

Study 2: BOTOX® n = 277; placebo n = 271

  • Patients with ≥50% reduction: BOTOX® 63.5%, placebo 33.2% (P <.001)
  • Patients with ≥75% reduction: BOTOX® 47.3%, placebo 20.3% (P <.001)
  • Patients with 100% reduction: BOTOX® 31.4%, placebo 10.3% (P <.001)

Study 3: BOTOX® n = 145; placebo n = 60

  • Patients with ≥50% reduction: BOTOX® 77.2%, placebo 33.3% (P <.001)
  • Patients with ≥75% reduction: BOTOX® 55.2%, placebo 21.7% (P <.001)
  • Patients with 100% reduction: BOTOX® 33.8%, placebo 11.7% (P < .001)

Results in Action

By significantly reducing daily leakage episodes, BOTOX® treatment may make a positive impact on your daily life.

Based on results of a questionnaire completed by patients in the BOTOX® clinical trials, patients on BOTOX® reported improvement in their overall quality of life. This questionnaire asked patients to consider three specific categories that are commonly important to people living with Overactive Bladder.

Avoidance and Limiting Behavior

Such as overplanning every detail of your day in advance. Including worrying about where bathrooms are and/or limiting how much fluid you drink.

Social Embarrassment

Such as being embarrassed or worried that your symptoms might be noticed by others.

Psychosocial Impact

Such as being preoccupied or frustrated with how your condition impacts your everyday decisions, such as what you can wear, where you can go, and how you feel about your overall well-being.

These improvements were reported using the Incontinence Quality of Life (IQOL) questionnaire. This is a validated questionnaire that is used to measure the impact of urinary incontinence on a patient's quality of life.

How well does BOTOX® work?

Watch the video to learn more.
 

Ready to talk to your doctor about BOTOX® treatment?

Download the Doctor Discussion Guide