About BOTOX® for OAB

Targets the Source of OAB

BOTOX® Targets the Source of
Overactive Bladder (OAB)

BOTOX® takes a different approach from other medications

BOTOX® targets OAB at its source by being placed in the bladder without the need for surgery, weekly doctor visits, or daily OAB pills.*

*Anticholinergic.

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Learn more about how BOTOX® works.

Expect more from your OAB treatment

Twice yearly BOTOX® treatment* gives you freedom from daily OAB pills that are intolerable or not working well enough.

*If OAB symptoms return before 6 months, talk to your doctor. A minimum of 12 weeks is needed between treatments.

Anticholinergic.

I thought my overactive bladder symptoms were just something I was going to have to live with somehow.”

— Marie

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Hear why real patients started on BOTOX®.

BOTOX® Reduces Daily Leakage Episodes

BOTOX® could be an OAB treatment you’ve been searching for

It is proven to work when other OAB medications did not

BOTOX® can be used in adults who have an inadequate response to or are intolerant of an anticholinergic medication. BOTOX® was proven to reduce daily leakage episodes at week 12.

Just 1 treatment significantly reduced daily leakage episodes

 

BOTOX® was proven to significantly reduce daily leakage episodes after the first treatment

In clinical trials, results were measured at 2, 6, and 12 weeks, with 12 weeks being the primary time point.

In clinical trials,

MONTHS AFTER TREATMENT

People treated with BOTOX® had an average of

FEWER LEAKAGE EPISODES PER DAY

Compared to 1 fewer leakage episode per day with placebo

You may notice results as soon as 2 weeks after treatment

People who experienced a reduction in daily
leakage episodes with BOTOX®

3 months after treatment in clinical trials*:

 

Limitation: The percentage of patients achieving 50% to 100% reduction in daily leakage episodes shown above was an additional measure in the primary clinical studies.

*These results are based on an analysis of the primary clinical data (reduction in daily leakage episodes). No definitive conclusions about the treatment effects with BOTOX® can be drawn from these results.

Study 1: BOTOX® n = 280, placebo n = 277;
Study 2: BOTOX® n = 277, placebo n = 271:

  • Patients with ≥ 50% reduction: BOTOX® 57.5% and 63.5%; placebo 28.9% and 33.2%
  • Patients with ≥ 75% reduction: BOTOX® 44.6% and 47.3%; placebo 15.2% and 20.3%
  • Patients with 100% reduction: BOTOX® 22.9% and 31.4%; placebo 6.5% and 10.3%

Approximately 1 in 4 people reported leakage episodes stopped completely

Talk to your doctor about switching to BOTOX® or find a BOTOX® Specialist near you

BOTOX® may positively impact your daily life by
significantly reducing leakage episodes

In BOTOX® clinical trials, a questionnaire showed:

Patients reported improvement in their overall
quality of life based on 3 categories*

Avoiding situations and
limiting behaviors

Overplanning daily details, concern about bathroom accessibility, and limiting how much they drink

Social and
psychological impact

Preoccupation with symptoms in everyday decisions, such as clothing and travel choices as well as their perceived overall well-being

Social
embarrassment

Self-consciousness or worry that others may notice their symptoms

Limitation: I-QOL was an additional measure in the primary clinical studies.

*This improvement was reported using the Incontinence Quality of Life (I-QOL) questionnaire. This is a validated questionnaire that is used to measure the impact of urinary incontinence on a patient’s quality of life.

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